Leucine absorption after jejunoileal bypass in rats

O. Carreras
M.L. Murillo
M.J. Delgado
J. Bolufer
82

Abstract

Jejunal and ileal absorption of L-leucine has been studied in rats subjected to jejunoileal bypass and in sham-operated rats, for five minute periods, using a perfusion technique.Aminoacid concentrations were: 1, 2.5, 5, 10 and 25 mM.In some experiments methionine was added to determine simple diffusion.The ratio of the active/diffusive components of absorption were calculated at the different luminal aminoacid concentrations in both groups of rats, showing that this ratio was lower in control animals.

Keywords:
Jejunoileal Bypass, Active, Animals, Biological Transport, Ileum/metabolism, Inbred Strains, Intestinal Mucosa/metabolism, Jejunum/metabolism, Leucine/pharmacokinetics, Male, Rats

Authors

O. Carreras
M.L. Murillo
M.J. Delgado
J. Bolufer


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