Reversible modification of rat liver F1-ATPase by a redox reaction

Abstract
F1-ATPase from rat liver mitochondria exhibited a change in properties when reduced by dithionite: an increase in activity together with a disappearance of its sensitivity to bicarbonate stimulation was observed. A complete reversion to the original properties was achieved with the oxidizing agent 2,6-dichlorophenolindophenol.
Keywords:
Adenosine Triphosphatases/metabolism, Animals, Bicarbonates/pharmacology, Chelating Agents/pharmacology, Dithionite/metabolism/pharmacology, Enzyme Activation, Liver/enzymology, Mitochondria, Oxidation-Reduction, Rats, Sulfites/metabolism
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