Genetic determination of coat color affects testicular steroidogenesis in the Mustela vison
Article Sidebar
14)How to Cite
63
Abstract
Coat color genes in mammals are known to be developmental genes with wide pleiotropic effects. The present study was undertaken to study testicular steroidogenesis in American Mink {Mustela vison) of various coat color phenotypes. No differences in testicular steroid levels were observed between fertile and infertile mink with the standard phenotype and genotype (BB jj MM PP). Mink with the opaline phenotype and genotype (bb mm pp), were found to have in their testes, 20-40 % higher levels of progesterone, five times higher levels of 17-hydroxyprogesterone, and eight times higher levels of testosterone, than the corresponding values in other mink. No other differences were observed among the different types of mink. Since the genotype of the opaline mink differs from the other mink studied, only in their combination at the pastel (b) and moyle (m) loci, their bb mm genotype could be assumed to be responsible for the increase in testicular steroids.
Authors
References
Amador, A. G., Bartke, A. and Hodges, S. L. (1988): Genome, 30 (suppl. 1), 259.
Amador, A. G., Klemcke, H. G. and Bartke, A. (1984): J. Androl., 5, 19P.
Amador, A. G. and Hodges, S. L. (1989): Comput.Biol. Med., 19, 343-354. https://doi.org/10.1016/0010-4825(89)90055-3
Amador, A. G., Levin, M., Huck, U. W., Hilgers, R. D. and Angel, N. (1993): Rev. esp.Fisiol., 49, 175-180.
Amador, A. G., Parkening, T., Beamer, W., Bartke, A. and Collins, T. J. (1984): J. Recept.Res., 4, 741-753. https://doi.org/10.3109/10799898409041862
Amador, A. G., Parkening, T. A., Collins, T. J., Bartke, A. and Silverman, A. Y. (1987): Adv. Contracep. Deliv. Syst., 3, 29-33.
Amador, A. G., Siler-Khodr, T. M., Mayerhofer, A., Steger R. W. and Bartke, A. (1989): Genetics, 122, s32.
Fantl, W. J., Johnson, D. E. and Williams, L. T. (1993): Ann. Rev. Biochem., 62, 453-481. https://doi.org/10.1146/annurev.bi.62.070193.002321
Nemetallah, B. R., Howell, R. E. and Ellis, L. C. (1985): Arch. Androl., 15, 79-82. https://doi.org/10.3109/01485018508986895
Norusis, M. J. (1987): The SPSS Guide to Data Analysis for SPSS-X. Chicago:SPSS Inc.
Robinson R. (1979): In "Vertebrates of Genetic Interest" (Handbook of Genetics, Vol. 4). Plenum Press, New York, NY, pp. 367-397.
Sokal, R. R. and Rohlf, F. J. (1981): Biometry (2nd), W. H. Freeman and Co., San Francisco, Ca.
Sundqvist, C., Amador, A. G. and Bartke, A. (1989): J. Reprod. Fert., 85, 413-441. https://doi.org/10.1530/jrf.0.0850413
Tung, K. S. K., Ellis, L. C., Teuscher, A., Meng, A., Blaustein, J. C., Kohno, S. and Howell, R. (1981): J. Exp. Med., 154, 1016-1032. https://doi.org/10.1084/jem.154.4.1016
Tung, K. S. K" Ellis, L. C., Childs, G. V. and Dufau, M. (1984): Endocrinology, 114, 922-929. https://doi.org/10.1210/endo-114-3-922
Tung, K. S. K., Teuscher, C., Smith, S., Ellis, L. and Dufau, M. L. (1985): Ann. N. Y. Acad. Sci., 438, 171-188. https://doi.org/10.1111/j.1749-6632.1984.tb38285.x
Van der Geer, P., Hunter, T. and Lindberg, R. A. (1994): Ann. Rev. Cell Biol., 10, 251-337. https://doi.org/10.1146/annurev.cb.10.110194.001343
Metrics
|
|