Variations of erythrocyte membrane proteins in cirrhotic patients

Abstract

The serum and erythrocyte membrane proteins of patients with cirrhosis were studied. Recent work on abnormalities of the erythrocyte membrane resulted in the identification of several types of membrane skeleton lesions. The different techniques for separation of membrane proteins have been revised and compared. These were studied on slabs using the SDS-polyacrylamide gel and discontinuous buffer system with a linear concentration gradient of 5-15% (w/v). Serum proteins were separated by using continuous buffer system with a linear concentration gradient of 4-30%. A decreased in serum and red cell membrane proteins in those patients, were observed.