Acute alcoholic intoxication and naloxone. Effects on visual evoked potential

M.S. Dawid-Milner
E.J. Díaz-Calavia
R. Fernández del Moral
J. Jiménez-Vargas
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Abstract

Experimental assays analyzing visual evoked potential (VEP) changes during an acute alcoholic intoxication were carried out in two groups of cats: One with continuous ethanol (0.06 g/kg.min) i.v. perfusion. Another one with a naloxone (400 micrograms/kg) i.v. injection 10 min before ethylic perfusion. Naloxone potentiates alcohol effects on VEP parameters, and on the appearance of isoelectric postpotential and flat VEP.

Keywords:
Acute Disease, Alcoholic Intoxication/physiopathology, Animals, Cats, Evoked Potentials, Male, Naloxone/pharmacology, Visual/drug effects

Authors

M.S. Dawid-Milner
E.J. Díaz-Calavia
R. Fernández del Moral
J. Jiménez-Vargas


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