Effect of gamma-hexachlorocyclohexane (Lindane) on the brain and serum tryptophan

M. Aldegunde
M. Parafita
M.P. Fernández-Otero
46

Abstract

The effect of convulsant doses of gamma-hexachlorocyclohexane (Lindane) on the brain and serum tryptophan contents as well as on the serum FFA contents was studied.The results indicate a possible correlation between the fluctuations in the FFA, free serum and brain tryptophan concentrations.The total tryptophan concentrations increase as well as the brain tryptophan/free tryptophan ratio, with both experimental doses.

Keywords:
Brain Chemistry, Animals, Brain/metabolism, Fatty Acids, Female, Hexachlorocyclohexane/pharmacology, Nonesterified/blood, Rats, Tryptophan/blood

Authors

M. Aldegunde
M. Parafita
M.P. Fernández-Otero


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