Stimulation of the hydrolytic activity of Na+,K+-ATPase in the erythrocytes by arginine vasopressin

Abstract
The effects of arginine vasopressin (AVP) on Na+,K+-ATPase activity in human erythrocytes have been studied.AVP stimulates enzymatic activity with no effect on transport activity.Since the enzymatic reaction with AVP can proceed in the absence of ion transport, it may explain the discrepancies between the in vivo and in vitro effects observed with the hormone on Na+ processing by the kidney.
Keywords:
Arginine Vasopressin/pharmacology, Biological Transport/drug effects, Erythrocytes/drug effects/enzymology, Humans, Hydrolysis, In Vitro Techniques, Sodium-Potassium-Exchanging ATPase/blood, Sodium/metabolism
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