Effects of short term experimental diabetes on brain serotonin metabolism
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27)
Published:
1988-09-01
Keywords:
Animals, Brain/metabolism, Diabetes Mellitus, Experimental/metabolism, Inbred Strains, Male, Rats, Serotonin/metabolism, Time Factors, Tryptophan/metabolism
How to Cite
Effects of short term experimental diabetes on brain serotonin metabolism. (1988). Revista Española De Fisiología, 44(3), 279-282. https://revistas.unav.edu/index.php/ref/article/view/46581
49
Abstract
Serotonin metabolism was studied in several brain regions of control and Streptozotocin-treated male Wistar rats.After induction of diabetes, the animals were killed at 24 hours.Concentrations of brain tryptophan show a generalized increase in all brain regions, being only significant in medulla-pons.Serotonin levels do not change, while 5-HIAA concentrations, as well as the ratio 5-HIAA/5-HT, show significant increases in medulla-pons and mid-brain.
Keywords:
Animals, Brain/metabolism, Diabetes Mellitus, Experimental/metabolism, Inbred Strains, Male, Rats, Serotonin/metabolism, Time Factors, Tryptophan/metabolism
Authors
G. Atienza
M. Aldegunde
J.A. Veira
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