Somatostatin does not modify 3-oxymethylglucose and leucine uptake by rat enterocytes

Abstract
The effects of somatostatin on 3-oxymethylglucose (3-OMG) and leucine uptake by rat enterocytes were examined.Somatostatin did not decrease the 3-OMG enterocyte uptake.When the 3-OMG active transport was inhibited by phloridzin, Somatostatin presented no significant modifications.Somatostatin showed a slight decrease in 3-OMG release through the basolateral membrane, when such a release was inhibited with theophylline.Somatostatin did not modify the intestinal leucine uptake or its inhibition by methionine.
Keywords:
3-O-Methylglucose, Active/drug effects, Animals, Biological Transport, Female, Inbred Strains, Intestinal Mucosa/metabolism, Intestines/drug effects, Leucine/pharmacokinetics, Male, Methylglucosides/pharmacokinetics, Methylglycosides/pharmacokinetics, Rats, Somatostatin/pharmacology
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