Malnutrition in utero and lactation: relation between the weight gained by the mothers and the development of their offspring

Abstract

Physiological weight changes in rat dams and their offspring as sequelae of malnutrition during pregnancy and lactation have been studied.Daily monitoring of the body weight as well as the consumption of food (malnutrition dams 14 g during pregnancy and 20 g during lactation) and drink in control and malnutrition dams was conducted.The number of pregnant dams that completed their pregnant period successfully was registered as well as the number and weight of the pups at birth and their evolution over a period of a month.The percentage of mortality of the pups during that period has been studied.The present results indicate a highly significant decrease in body weight in experimental dams, which determines a retardation in the physiological development of the pups, and yields a higher percentage of mortality in the experimental animals than in controls.It can thus be concluded that malnutrition in utero and during lactation affects the ratio between weight gain for dams and the physical development of their pups.