Adrenovascular alterations from neurogenic stress modified by denervation of the adrenal gland in rat

Abstract

The application of a painful stimulus to restrained rats provokes conspicuous adrenovascular alterations (vasodilatation, edema, small hemorrhages).Hypophysectomy does not prevent the adrenovascular response to stress, or the abdominal vagotomy.On the contrary, splanchnicotomy practically abolishes such response.These results show that the vascular alterations, consequence of the action of a neurogenic stress, are not caused by a hypophysohormonal response but by a sympathetic one.