NKCELPRO: a program for microcomputer applicable to the study of responses of spontaneous cytotoxicity

Abstract

A microcomputer program (NKCELPRO) which expedites the exact quantification of various parameters referring to NK cell activities is described.The program is written in BASIC language and computes the activities of cell-mediated cytotoxicity by collating and reducing radioactive count data obtained from 51Cr releasing assays.The information generated by this program includes statistics such as the average values, fitting by last square regression line with its correlation coefficient, as well as determination of the percent specific lysis and lytic units/10(7) effector cells according to any reference value previously defined by the operator.Special program features allow for a certain flexibility in the experimental protocol design as well as in the graphic expression of the results.Data storage on a disk with filing purposes for subsequent studies is also available.