Effect of inanition on the glucosaminoglucans of the skin and trachea of rats

Abstract

Effect of Inanition on Glucosamineglucans of the Skin and Trachea of Rats

The effect of different periods of inani­tion on the glucosamineglucans concentration in skin and trachea of male Wistar rats was studied. 24 hours prior to killing animáis were injected with S3S-sulfate (1 Mc/Kg B.W.).

Total uronic acids and specific activity were determined on the isolated glucosaminoghicans from trachea and abdominal skin. Uronic acid concentration decreases in both tissues after three-four days of inanition. Tliis diminution is due mainly to a decrease in hyaluronic acid concen­ tration, with no changes in the sulfated fraction.

Specific activity of S35-sulfate in skin shows a decrease after 3-4 days of inanition, remaining the tracheal cartilage without changes.