Failure of oxytocin and vasopressin to combine with an anti-insulin antibody

Abstract

Synthetic oxytocin and vasopressin do not exert an insulinlike action in combin­ing with an ox anti-insulin serum. Since the only characteristic of both insulin and these peptides is the presence of a disulfi­de bridge, it became pertinent to show that these particular portions of the mo­lecule per se, do not play a role in the antigen-antibody reaction.