Effect of intestine irradiation in the absence of sodium on the oxygen uptake

Abstract

The effect of X-irradiation (20.000 r) was studied in vitro in jejunum strips pre­ incubated in medium without sodium over the posterior oxygen uptake of the tissue in medium with sodium, with and without glucose.

Irradiation under these conditions inhibits oxygen consumption by the tissue, the medium both with and without substrate, oxygen uptake reaching values much lower than those obtained with equal dosage of irradiation combined with medium with sodium. The inhibition produced by irradiation and that produced by preincubation in medium without sodium add their effects when these factors act simultaneously.