Urinary protein components. III. Classification of proteinuria based on the protein clearance results

B. Pinto
P. Barceló
34

Abstract

Six stages or grades of the kidney protein selectivity are described, according to number and kind of proteins appeared in the urine, the net clearances, the curve profiles, the slope and the glomerular sieving coefficients. Respective data of stages IV, V and VI are in strong contradiction to the one single site protein tubular absorption hypothesis. A four mechanisms scheme is proposed depending upon the glomerular sieving and tubular absorption combined activities.

Keywords:
Albumins/analysis, Electrophoresis, Glomerular Filtration Rate, Humans, Immunodiffusion, Immunoelectrophoresis, Macroglobulins/analysis, Proteinuria/classification, gamma-Globulins/analysis

Authors

B. Pinto
P. Barceló


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