Inhibition of insulin secretion in vitro by somatostatin
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29)
Published:
1974-12-01
Keywords:
Animals, Chemical, Glucose/pharmacology, Growth Hormone/antagonists and inhibitors, Insulin Antagonists, Insulin Secretion, Insulin/metabolism, Pancreas/physiology, Peptides/pharmacology, Rats, Stimulation, Time Factors
How to Cite
Inhibition of insulin secretion in vitro by somatostatin. (1974). Revista Española De Fisiología, 30(4), 299-301. https://revistas.unav.edu/index.php/ref/article/view/49391
52
Abstract
Inhibition of Insulin Secretion in vitro by Somatostatin. Rev. esp. Fisiol., 30, 299-302. 1974.
The isolated and perfused rat páncreas was used to study the insulin secretion stimulated by 16.7 mM glucose in the presence of SRIF (somatotropin release inhibiting factor); at a concentration of 2 /xg/ml, the latter was a potent inhibitor of insulin secretion. Since SRIF is effective in inhibiting growth hormone and glucagon secretion also, the secretory mechanism of the three hormones may have a common basis.
Keywords:
Animals, Chemical, Glucose/pharmacology, Growth Hormone/antagonists and inhibitors, Insulin Antagonists, Insulin Secretion, Insulin/metabolism, Pancreas/physiology, Peptides/pharmacology, Rats, Stimulation, Time Factors
Authors
J. Tamarit
J. Tamarit-Rodríguez
R. Goberna
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