Hypoglycaemic activity of centaurea aspera L

J.L. Massó; T. Adzet

J.L. Massó

T. Adzet

PDF (Spanish) (

18)

Published: 1976-12-01

Keywords:

Administration, Animals, Diabetes Mellitus, Diabetes Mellitus/drug therapy, Experimental/drug therapy, Female, Glyburide/therapeutic use, Hypoglycemic Agents/analysis, Injections, Intravenous, Male, Medicinal/analysis, Mice, Oral, Plant Extracts/analysis/therapeutic use, Plants

How to Cite

Hypoglycaemic activity of centaurea aspera L. (1976). Revista Española De Fisiología, 32(4), 313-316. https://revistas.unav.edu/index.php/ref/article/view/49478

59

Abstract

Two aquous crude extracts of Centaurea aspera L. flowers were tested for hypoglycaemic activity in normal and alloxan-diabetic rats. Both extracts exert a significant hypoglycaemic effect by oral route and chronic administration in diabetic rats, but only the extract obtained by exhaustion with hot water displayed an acute hypoglycaemic activity in normal animals. All plant-treated groups were compared against glibenclamide as a standard. The acute toxicity by oral and intravenous routes was determined in mice.

Keywords:

Administration, Animals, Diabetes Mellitus, Diabetes Mellitus/drug therapy, Experimental/drug therapy, Female, Glyburide/therapeutic use, Hypoglycemic Agents/analysis, Injections, Intravenous, Male, Medicinal/analysis, Mice, Oral, Plant Extracts/analysis/therapeutic use, Plants