Effect of somatostatin on renin secretion in the isolated perfused rat kidney

T. Quesada
C.G. del Río
F. Alba
M. de la Torre
J. Osorio
34

Abstract

The effects of tetradecapeptide somatostatin on renin secretion has been studied in the isolated perfused kidney of the rat. The stimulation mediated by isoproterenol (7 X 10(-9) M), theophylline (10(-4) M) and PGE2 (10 ng/ml) was not inhibited by somatostatin (75 ng/ml).

Keywords:
Animals, Cancer, Chemical, Chemotherapy, Isoproterenol/pharmacology, Kidney/drug effects/physiology, Rats, Regional Perfusion, Renin/metabolism, Somatostatin/pharmacology, Stimulation, Theophylline/pharmacology

Authors

T. Quesada
C.G. del Río
F. Alba
M. de la Torre
J. Osorio


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