Effect of somatostatin on renin secretion in the isolated perfused rat kidney

Abstract
The effects of tetradecapeptide somatostatin on renin secretion has been studied in the isolated perfused kidney of the rat. The stimulation mediated by isoproterenol (7 X 10(-9) M), theophylline (10(-4) M) and PGE2 (10 ng/ml) was not inhibited by somatostatin (75 ng/ml).
Keywords:
Animals, Cancer, Chemical, Chemotherapy, Isoproterenol/pharmacology, Kidney/drug effects/physiology, Rats, Regional Perfusion, Renin/metabolism, Somatostatin/pharmacology, Stimulation, Theophylline/pharmacology
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