Experimental cardiogenic shock

Abstract

An experimental model fo cardiogenic shock has been developed in anesthetized dogs. The shock was produced by injecting mercury into the second diagonal branch of the descending anterior coronary artery. Arterial and venous pressure E.C.G., aortic, renal and circumflex flow were directly measured. Other parameters such as O2 consumption and arterio-venous difference were also studied. The present model seems very useful to make therapeutic studies. Open chest surgery has been used for simplicity and economic reasons.