An index of protein hydrophobicity. Its application to membrane proteins

J.C. Gómez
M.A. Ventura
F.M. Goñi
E. Santiago
54

Abstract

A hydrophobicity index is proposed for proteins. The calculation of this index is made, assuming a direct relationship between the hydrophobicity of each aminoacid and its Rf in a partition chromatography. This index is applied to membrane proteins and offers statistically significant differences between integral and peripheral proteins.

Keywords:
Amino Acids/analysis, Analysis of Variance, Chromatography, Membrane Proteins/analysis, Water/analysis

Authors

J.C. Gómez
M.A. Ventura
F.M. Goñi
E. Santiago


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