Studies on the fine structure of the rat liver inner mitochondrial membranes negatively stained

Abstract

Isolated inner membranes of rat liver mitochondria were fixed with osmium te­troxide and examined by electron micro­scopy after negative staining. Two types of structures were observed: tubules and lamellae. The tubules showed the typical projecting subunits covering their entire outer surface. Lamellae represent a minor component and they completely lack pro­jecting subunits. Frequently tubular ma­terial is found to join lamellar areas. The point of junction is ofter funnel shaped.