Angiotensin II effects on plasmatic renin activity

F.J. Rodriguez
J. Simón
J. Yajeya
66

Abstract

Intravenous infusion of angiotensin II into the cat (4.13 microng/45 min) produces a decrease of plasmatic renin activity. This reduction was not modified after the bilateral denervation of the kidneys or section of both carotid and aortic nerves. The reserpinization of the cats does not modify the angiotensin effects on the renin plasmatic concentration. These observations suggest that the sympathetic nervous system and the catecholamines do not alter significantly the effects of angiotensin II on the renin secretion.

Keywords:
Angiotensin II/administration and dosage/pharmacology, Animals, Cats, Chemical, Denervation, Kidney/innervation, Renin/antagonists and inhibitors/blood/metabolism, Secretory Rate/drug effects, Stimulation, Sympathetic Nervous System/metabolism/physiology

Authors

F.J. Rodriguez
J. Simón
J. Yajeya


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