Myelopoiesis in lymph nodes of mice treated with trypan blue

P. Sesma
50

Abstract

When mice are injected with trypan blue inside the peritoneal cavity immediately after birth, a delay of the lymphocyte colonization and an enhancement of the lymph node myelopoiesis are observed. In normal mice some granulopoiesis takes place in lymph nodes between 4th and 12th days after birth, but after trypan blue treatment granulopoiesis increases and erythroid colonies appear. These findings indicate that the blockade of RES enhances the hemopoiesis in lymph nodes.

Keywords:
Animals, Erythropoiesis/drug effects, Granulocytes/drug effects, Injections, Intraperitoneal, Lymph Nodes/cytology/growth and development, Mice, Trypan Blue/pharmacology

Authors

P. Sesma


Metrics

Search GoogleScholar



Downloads

Download data is not yet available.

Section

Articles