Prolactin receptors and breast cancer

Abstract
A study has been carried out on 116 mammary neoplasias in which the prolactin receptors together with other clinical and hormonal parameters have been determined. A 46.3% frequency of PRLR+ has been obtained as well as a statistically significant correlation between these and blood estradiol (p less than 0.05). PRLR- have greater survival and PRLR may act as a growth factor.
Keywords:
Prolactin/blood, Breast Neoplasms/analysis/physiopathology, Dehydroepiandrosterone/blood, Estradiol/blood, Female, Hormone-Dependent/analysis/physiopathology, Humans, Neoplasms, Progesterone/blood, Prognosis, Prolactin/analysis/physiology, Receptors
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