Serum androgen levels after streptozotocin administration in the male rat

I. Centol
F. López-Blanco
A. Deniz
L. Benítez
I. Marrero-Arencibia
L. Fanjul
C.M. de Galarreta
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Abstract

Serum levels of testosterone and dihydrotestosterone were measured in control and diabetic animals 5, 10 and 15 days after streptozotocin administration.The diabetic state produced a marked reduction in serum androgen levels 10 and 15 days after streptozotocin administration.Insulin treatment partially restored the circulating androgen levels when administered to diabetic rats.

Keywords:
Animals, Diabetes Mellitus, Dihydrotestosterone/blood, Experimental/blood, Inbred Strains, Male, Rats, Streptozocin/pharmacology, Testosterone/blood

Authors

I. Centol
F. López-Blanco
A. Deniz
L. Benítez
I. Marrero-Arencibia
L. Fanjul
C.M. de Galarreta


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