Effect of LH-RH, gonadotrophins or sex hormones on protein synthesis in hypothalamus and pituitaryof immature female rat in vitro

B.N. Díaz-Chico
J.C. Díaz-Chico
M.E. Díaz-Díaz
41

Abstract

Protein synthesis in cerebral cortex, hypothalamus and pituitary of immature female rats was studied after treatment with 5 doses of LH-RH, gonadotrophins or sex hormones.None of the hormonal doses affected protein synthesis in cortex.Sex hormones and gonadotrophins increased protein synthesis in hypothalamus.These effects are attributed to positive feed-backs of these hormone on immature female rat hypothalamus.All treatments increased protein synthesis in pituitary.The direct effect of LH-RH on pituitary and the feed-back effect of sex hormones or gonadotrophins are compared and discussed.

Keywords:
Protein Biosynthesis, Animals, Female, Gonadal Steroid Hormones/metabolism, Gonadotropin-Releasing Hormone/metabolism, Gonadotropins/metabolism, Hypothalamo-Hypophyseal System/metabolism, In Vitro Techniques, Rats

Authors

B.N. Díaz-Chico
J.C. Díaz-Chico
M.E. Díaz-Díaz


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