Effect of manganese poisoning on the levels of manganese and iron in rat viscera

Abstract
Twenty rats were poisoned by manganese inhalation, and sacrificed six months after the first exposure.The tissue concentrations (in microgram/g dry weight) of manganese and iron were found in liver, pancreas, lung, kidney and suprarenal gland for atomic absorption spectrometry in control and experimental animals.The measurements show high tissue concentrations of manganese, especially in liver and pancreas of the experimental animals, as well as a little increase in the tissue concentrations of iron, fundamentally in liver, kidney and suprarenal gland.
Keywords:
Adrenal Glands/metabolism, Animals, Inbred Strains, Iron/metabolism, Kidney/metabolism, Liver/metabolism, Lung/metabolism, Manganese Poisoning, Manganese/metabolism, Pancreas/metabolism, Rats
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