Cortisol influence on some typical parameters of protein malnutrition in rats

Abstract

A daily v.s.dose of cortisol administered to rats, induces certain metabolic modifications, which after using the "pair-fed" system have been proven to be at least partially independent of the ingesta decrease originated by cortisol.Both cortisol treatment and experimental proteic malnutrition, originate a decrease in corporal weight, a lessening of the gamma-globulins plasmatic fraction, and an elimination increase in total nitrogen, protein, creatine and creatinine in urine.Cortisol treatment determines an increase in blood red cells number, as well as an increase in total serum proteins, especially albumin, without provoking a lessening in the beta-globulins fraction, as happens in cases of proteic malnutrition.