Effects of the x-irradiation in vitro on the O2 uptake and on the utilization of glucose by the intestine

Abstract

The exposure of strips of rat jejunum mantained in vitro to X-rays (20.000 r), inhibits the posterior oxygen consumption of the tissues with or without glucose in the medium. The utilization of glucose also decreases, while the production of lactate is not noticeable modified. An explanation of these facts is given on the basis of the alteration of cell respiratory systems on account of the irradiation, in­ dependently of the inhibition produced on the sugar active transport.