NADH-cytochrome c reductase, succinate cytochrome c reductase and phospholipids

E. Santiago; N. López-Moratalla; J.L. Segovia; J. Eugui

E. Santiago

N. López-Moratalla

J.L. Segovia

J. Eugui

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Published: 1977-09-01

Keywords:

Animals, Ascorbic Acid/metabolism, Cytochrome Reductases/metabolism, Flavins/metabolism, Liver/enzymology, Membranes/enzymology, Microsomes, NADPH-Ferrihemoprotein Reductase/metabolism, Oxidoreductases/metabolism, Phosphatidylcholines/physiology, Phosphatidylethanolamines/physiology, Rats, Succinate Cytochrome c Oxidoreductase/metabolism, Ubiquinone/metabolism

How to Cite

NADH-cytochrome c reductase, succinate cytochrome c reductase and phospholipids. (1977). Revista Española De Fisiología, 33(3), 197-204. https://revistas.unav.edu/index.php/ref/article/view/49577

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Abstract

Phospholipid peroxidation of isolated rat liver inner mitochondrial membranes induced by either ascorbate or cysteine was accompanied by a release of flavins and coenzyme Q. A straight correlation between this release and the alteration of molecular species of phosphatidylcholine and phosphatidylethanolamine containing one saturated and one unsaturated fatty acid has been found. Peroxidation induced on molecular species of phosphatidylcholine and phosphatidylethanolamine containing only unsaturated fatty acids were accompanied by losses in enzyme activities of NADH-cytochrome c reductase and succinate cytochrome c reductase.

Keywords:

Animals, Ascorbic Acid/metabolism, Cytochrome Reductases/metabolism, Flavins/metabolism, Liver/enzymology, Membranes/enzymology, Microsomes, NADPH-Ferrihemoprotein Reductase/metabolism, Oxidoreductases/metabolism, Phosphatidylcholines/physiology, Phosphatidylethanolamines/physiology, Rats, Succinate Cytochrome c Oxidoreductase/metabolism, Ubiquinone/metabolism