Strain-specific antigens detected on murine tumour cells by means of rabbit heteroantisera

E. García-Olivares
F. Garrido
F. Gutiérrez
C. Osorio
42

Abstract

The rabbit heteroantisera anti-Meth A sarcoma (H-2d) (RAMA) and rabbit anti-RBL-5 leukemia (H-2b) (RAR-5) have been used to study the presence of normal strain antigens on the surface of different murine tumour cells. RAR-5 detected H-2-like structures on TLX9 (H-bb) lymphoma, however RAMA did not on LSTRA leukemia (H-2d) mastocytoma. Neither RAR-5 nor RAMA contained antibodies against non-H-2 and differentiation antigens.

Keywords:
Animals, Antibodies, Antigens, Experimental/immunology, Heterophile/analysis, Inbred Strains/immunology, Leukemia, Mice, Rabbits, Sarcoma

Authors

E. García-Olivares
F. Garrido
F. Gutiérrez
C. Osorio


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