Lack of effect of alpha-tocopherol and ascorbic acid on the response of some physiological variables to immobilization stress in rat
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21)
Published:
1989-09-01
Keywords:
Adrenocorticotropic Hormone/blood, Animals, Ascorbic Acid/pharmacology, Corticosterone/blood, Drug Synergism, Inbred Strains, Lactates/blood, Lactic Acid, Male, Physical, Physiological/blood/physiopathology, Rats, Restraint, Stress, Vitamin E/pharmacology, Tocopherol, Pituitary-adrenal axis, Antioxidants
How to Cite
Lack of effect of alpha-tocopherol and ascorbic acid on the response of some physiological variables to immobilization stress in rat. (1989). Revista Española De Fisiología, 45(3), 277-280. https://revistas.unav.edu/index.php/ref/article/view/46569
45
Abstract
The effect of alpha-tocopherol or ascorbic acid jointly and separately on the seric levels of adrenocorticotropin (ACTH) and corticosterone has been studied.ACTH response to stress is similar in all groups, whereas the corticosterone response is higher in the animals treated with alpha-tocopherol.Neither lactate response nor gastric ulceration caused by stress was influenced by the administration of alpha-tocopherol and/or ascorbic acid.These results suggest that free radicals might not be implicated in the control of the physiological response to stress.
Keywords:
Adrenocorticotropic Hormone/blood, Animals, Ascorbic Acid/pharmacology, Corticosterone/blood, Drug Synergism, Inbred Strains, Lactates/blood, Lactic Acid, Male, Physical, Physiological/blood/physiopathology, Rats, Restraint, Stress, Vitamin E/pharmacology, Tocopherol, Pituitary-adrenal axis, Antioxidants
Authors
A. Armario
M. Borrás
L. Campmany
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