The endocochlear potential in experimental renal insufficiency

Abstract
Endocochlear Potential (EP) was measured in male Wistar rats under control conditions and renal failure produced by means of bilateral nephrectomy.Results show a statistically significant (p less than 0.01) decrease in EP measured in animals with renal failure.This finding is in accordance with the decrease in Na-K ATPase activity found in the cochlea and other structures in human and experimental kidney insufficiency.
Keywords:
Cochlear Microphonic Potentials, Evoked Potentials, Active, Animals, Auditory, Biological Transport, Chronic/physiopathology, Cochlea/enzymology/physiopathology, Inbred Strains, Kidney Failure, Male, Membrane Proteins/physiology, Rats, Sodium-Potassium-Exchanging ATPase/physiology
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