The endocochlear potential in experimental renal insufficiency

R. Urquiza
M. Morell
60

Abstract

Endocochlear Potential (EP) was measured in male Wistar rats under control conditions and renal failure produced by means of bilateral nephrectomy.Results show a statistically significant (p less than 0.01) decrease in EP measured in animals with renal failure.This finding is in accordance with the decrease in Na-K ATPase activity found in the cochlea and other structures in human and experimental kidney insufficiency.

Keywords:
Cochlear Microphonic Potentials, Evoked Potentials, Active, Animals, Auditory, Biological Transport, Chronic/physiopathology, Cochlea/enzymology/physiopathology, Inbred Strains, Kidney Failure, Male, Membrane Proteins/physiology, Rats, Sodium-Potassium-Exchanging ATPase/physiology

Authors

R. Urquiza
M. Morell


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