Inhibition of O2 uptake of rat jejunum by x-irradiation in vitro". Protection by cysteamine"

Abstract
A study has been made of the effect of X irradiation in vitro of strips of rat jejunum on the O”ž uptake of the tissue.
The X irradiation (50 KV, 1 mm Al, i,ouo rp.m.) produces a decrease in the O3 uptake which first appears after 2 or 3 hours of recording and becomes more apparent as time goes on. The effect can already be no ticed with 5,000 r and is greater at 10,000 and 20,000 r. We have also observed inhibi tion of the O. uptake when there is glucose (2.77 mM) in the medium.
The presence of cysteamine 0.02 M during the irradiation absolutely protects the preparations from these inhibitory effects on the uptake.
Keywords:
Oxygen Consumption, Radiation Effects, Animals, Cysteamine/pharmacology, Jejunum/metabolism/radiation effects, Rats
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