Effect of dicumarol on the intestinal absorption of sugars

Abstract

The in vivo technique of successive ab­ sorption was utilized to investigate the effect of Dicumarol on the intestinal ab­ sorption of D-glucose and L-arabinose.

A 10~4 M concentration of Dicumarol inhibits the absorption of glucose. This ef­ fect persists in a successive absorption without Dicumarol.

On the contrary, the absorption of L-arabinose is enhanced by Dicumarol when present in the sugar solution.