The effect of an synthetic heparinoid (SP-54) on platelet aggregation

J. Aznar
R. Baguena
J. Garcia-Conde
V. Alberola
47

Abstract




The antithrombotic activity of a syn­thetic heparinoid, SP-54, has been studied. It was demonstrated that the SP-54 at the­ rapeutical doses, prevents in vitro plate­lets from adhering to each other. It could suggest the use of this drug to prevent the thrombus formation in the thrombophilic state.




Keywords:
Animals, Blood Platelets/drug effects, Cell Aggregation/drug effects, Heparinoids/pharmacology, Platelet Adhesiveness/drug effects, Sheep

Authors

J. Aznar
R. Baguena
J. Garcia-Conde
V. Alberola


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