Effect of dipyridamol on the electrokinetic potential of platelets

J. Aznar
J. Vallés
41

Abstract




Effect of Dipyridamol on the Electrokinetic Potential of Platelets. Rev. esp. Fisiol., 30, 77-80. 1974.


The effect of different doses of dipyridamol on the electrokinetic potential of platelets has been studied in plasma from 31 normal subjects. As increase of the plate­ let migratory velocity was found, being statistically significant at 4 /xg/ml final con­ centration.


The possible implications of this increase as related to changes in the platelet membrane an the antiaggregating effect of dipyridamol are discussed.




Keywords:
Adenosine Diphosphate/pharmacology, Adenosine Triphosphatases/pharmacology, Adenosine/pharmacology, Binding Sites, Blood Platelets/drug effects/physiology, Cell Membrane/drug effects, Dipyridamole/pharmacology, Humans, Kinetics, Platelet Aggregation/drug effects, Time Factors

Authors

J. Aznar
J. Vallés


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