Distribution in tissues and effects by acute hypoxia on angiotensin I converting enzyme activity in guinea pig and chicken

C. Cuadrillero; M.J. Polanco; M.T. Agapito; J.M. Recio

C. Cuadrillero

M.J. Polanco

M.T. Agapito

J.M. Recio

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Published: 1984-09-01

Keywords:

Animals, Chickens, Diaphragm/enzymology, Dogs, Guinea Pigs, Hypoxia/enzymology, Kidney/enzymology, Lung/enzymology, Mice, Peptidyl-Dipeptidase A/analysis, Rabbits, Species Specificity, Angiotensin I Converting enzyme, Tissue distribution Guinea pig

How to Cite

Distribution in tissues and effects by acute hypoxia on angiotensin I converting enzyme activity in guinea pig and chicken. (1984). Revista Española De Fisiología, 40(3), 371-374. https://revistas.unav.edu/index.php/ref/article/view/46701

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Abstract

Angiotensin I converting enzyme activity was measured in homogenates of guinea pig and chicken organs (lung, kidney, heart, ileum, diaphragm and liver), using a spectrophotometric assay for hydrolysis of hippuryl-L-histidyl-L-leucine.High specific activities were found in lung, kidney and diaphragm, but the highest corresponded to guinea pig lung and chicken kidney.Acute hypoxia decreased angiotensin I converting enzyme activity in guinea pig lung and chicken diaphragm, but the changes in kidney were considered non-significant in both the guinea pig and chicken.

Keywords:

Animals, Chickens, Diaphragm/enzymology, Dogs, Guinea Pigs, Hypoxia/enzymology, Kidney/enzymology, Lung/enzymology, Mice, Peptidyl-Dipeptidase A/analysis, Rabbits, Species Specificity, Angiotensin I Converting enzyme, Tissue distribution Guinea pig