Distribution in tissues and effects by acute hypoxia on angiotensin I converting enzyme activity in guinea pig and chicken

C. Cuadrillero
M.J. Polanco
M.T. Agapito
J.M. Recio
36

Abstract

Angiotensin I converting enzyme activity was measured in homogenates of guinea pig and chicken organs (lung, kidney, heart, ileum, diaphragm and liver), using a spectrophotometric assay for hydrolysis of hippuryl-L-histidyl-L-leucine.High specific activities were found in lung, kidney and diaphragm, but the highest corresponded to guinea pig lung and chicken kidney.Acute hypoxia decreased angiotensin I converting enzyme activity in guinea pig lung and chicken diaphragm, but the changes in kidney were considered non-significant in both the guinea pig and chicken.

Keywords:
Animals, Chickens, Diaphragm/enzymology, Dogs, Guinea Pigs, Hypoxia/enzymology, Kidney/enzymology, Lung/enzymology, Mice, Peptidyl-Dipeptidase A/analysis, Rabbits, Species Specificity, Angiotensin I Converting enzyme, Tissue distribution Guinea pig

Authors

C. Cuadrillero
M.J. Polanco
M.T. Agapito
J.M. Recio


Metrics

Search GoogleScholar



Downloads

Download data is not yet available.

Section

Articles

Most read articles by the same author(s)

1 2 > >>