Effect of pineal indoles and testosterone on sex behavior

Abstract
The possible action of melatonin and 5-methoxytryptophol, two pineal indoles, upon castrated male rat sexual behaviour with three testosterone dose levels was studied.Both indoles reduced the number of mounts and intromissions.5-Methoxytryptophol, in addition, decreased the number of ejaculations.The sexual actions of the pineal indoles are prevented by the administration of high testosterone dose levels (500 micrograms/day).
Keywords:
Animal/drug effects, Animals, Castration, Dose-Response Relationship, Drug, Ejaculation/drug effects, Inbred Strains, Indoles/antagonists and inhibitors/pharmacology, Male, Melatonin/antagonists and inhibitors/pharmacology, Pineal Gland/physiology, Rats, Sexual Behavior, Testosterone/pharmacology, 5-Methoxytryptophol
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