Arginine as competitive inhibitor of argininosuccinate synthetase from guinea pig liver

G. Soler; F.J. Mataix; M. Ruiz-Amil

G. Soler

F.J. Mataix

M. Ruiz-Amil

PDF (

26)

Published: 1981-09-01

Keywords:

Animals, Arginine/pharmacology, Argininosuccinate Synthase/antagonists and inhibitors, Aspartate Ammonia-Lyase/metabolism, Citrulline/metabolism, Guinea Pigs, Kinetics, Ligases/antagonists and inhibitors, Liver/enzymology, Male

How to Cite

Arginine as competitive inhibitor of argininosuccinate synthetase from guinea pig liver. (1981). Revista Española De Fisiología, 37(3), 359-362. https://revistas.unav.edu/index.php/ref/article/view/47301

35

Abstract

The influence of arginine on arginosuccinate synthetase (E.C. 6.3.4.5) from guinea pig liver has been investigated. The results show a competitive inhibition by arginine with respect to the three substrates of the enzime: L-citrulline, L-aspartate and ATP.

Keywords:

Animals, Arginine/pharmacology, Argininosuccinate Synthase/antagonists and inhibitors, Aspartate Ammonia-Lyase/metabolism, Citrulline/metabolism, Guinea Pigs, Kinetics, Ligases/antagonists and inhibitors, Liver/enzymology, Male