Study of the KO-592 antagonism with isoproterenol in different affected areas

A.J. Brugger

A.J. Brugger

PDF (Spanish) (

14)

Published: 1967-03-01

Keywords:

Animals, Blood Pressure/drug effects, Cardiac Output/drug effects, Dogs, Female, Isoproterenol/antagonists and inhibitors, Propylamines/pharmacology, Sympathomimetics/pharmacology, Uterus/drug effects

How to Cite

Study of the KO-592 antagonism with isoproterenol in different affected areas. (1967). Revista Española De Fisiología, 23(1), 13-17. https://revistas.unav.edu/index.php/ref/article/view/49098

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Abstract

A study has been made of the KÖ- 592 (adrenolithic beta)-isoproterenol antagonism on arterial pressure, cardiac frequency and uterine motility, using anesthetized female dogs, previously subject to a uterine probe.

The antagonism between the two drugs has studied at molecular level in order to determine the nature of the same, and the conclusión has been reached that KÖ-592 is a competitive antagonism of aleudrine.

Keywords:

Animals, Blood Pressure/drug effects, Cardiac Output/drug effects, Dogs, Female, Isoproterenol/antagonists and inhibitors, Propylamines/pharmacology, Sympathomimetics/pharmacology, Uterus/drug effects