Isolation and structure determination of 2 isomers of eicosatrienoic acid of rat liver
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22)
Published:
1970-09-01
Keywords:
Animals, Dietary Fats/metabolism, Essential/metabolism, Fatty Acids, Fatty Acids/isolation and purification, Linoleic Acids/metabolism, Liver/metabolism, Male, Oxidation-Reduction, Phospholipids/metabolism, Rats
How to Cite
Isolation and structure determination of 2 isomers of eicosatrienoic acid of rat liver. (1970). Revista Española De Fisiología, 26(3), 245-252. https://revistas.unav.edu/index.php/ref/article/view/49221
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Abstract
The effect of feeding linoleate and linolenate together, upon the fatty acid compo- sition of liver phospholipids of weanling rats previously fed a fat free diet was investigated.
Feeding with linoleate and linolenate caused a decrease in fatty acids, whilst fatty acids synthezised from linoleate and linolenate were incorporated into phosphatides. The eicosatrienoic acid oleic type did not completely disappear, and was found together with a secón isomeric form which was not present in rats fed a fat free diet. The structure of the second isomer was determinated by both oxidative and reductive ozonolysis. It was found to be the A8>11,14-C20.3» which is an intermedíate product in the synthesis of arachidonic acid.
Keywords:
Animals, Dietary Fats/metabolism, Essential/metabolism, Fatty Acids, Fatty Acids/isolation and purification, Linoleic Acids/metabolism, Liver/metabolism, Male, Oxidation-Reduction, Phospholipids/metabolism, Rats
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