Localization of enzymes in blood protein fractions. I. Leucine aminopeptidase

E. Concustell-Bas
V. Villar-Palasi
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Abstract




Chromatographic separation of proteins by DBAE-cellulose in a number of normal sera has been performed. Tested theLAP activity in the different fractions, it has been localized in only one pick, placed in the región of the post-albumin and alpha globulins ; it shows the presence of an unic active mo­ lecular form of leucine aminopeptidase in normal sera.


On the other hand, it has been observed a LAP activity distribution in two and even three picks in different pathological sera.




Keywords:
AMINOPEPTIDASES, Aminopeptidases, BLOOD PROTEINS, Blood Proteins, Leucine, Leucyl Aminopeptidase, Physiological Phenomena, Saccharomyces cerevisiae Proteins, Humans

Authors

E. Concustell-Bas
V. Villar-Palasi


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