Clofibrate effect on thyroid function
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19)
Published:
1973-03-01
Keywords:
Animals, Chromatography, Clofibrate/pharmacology, Iodine Radioisotopes, Iodine/blood, Male, Organ Size, Paper, Propylthiouracil/pharmacology, Rats, Thyroid Function Tests, Thyroid Gland/drug effects/metabolism, Thyroxine-Binding Proteins, Thyroxine/biosynthesis/blood
How to Cite
Clofibrate effect on thyroid function. (1973). Revista Española De Fisiología, 29(1), 17-20. https://revistas.unav.edu/index.php/ref/article/view/49343
44
Abstract
Clofibrate (CF) administered for one month to PTU-treatcd rats íncreased thyroid uptake, PBI131 serie levels, thyroxin synthesis and thryroid stable iodine concentration. In another experiment, which was carried out during two months, CF normalized thyroid uptake and thyroxin synthesis in rats having taken PTU for the first month, and raised the thyroid iodine over the control valúes.
Nevertheless the PTU-goiter in both experiments was not modified by CF.
Keywords:
Animals, Chromatography, Clofibrate/pharmacology, Iodine Radioisotopes, Iodine/blood, Male, Organ Size, Paper, Propylthiouracil/pharmacology, Rats, Thyroid Function Tests, Thyroid Gland/drug effects/metabolism, Thyroxine-Binding Proteins, Thyroxine/biosynthesis/blood
Authors
M. Muñoz-Rodríguez
F.Torrano-San Francisco
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