Applications of polarography to diagnosis of malignant tumors

Abstract

137 polarogrames have been accomplished in patients, with the followings results:

The serum of patients affected of malignant thumors in evolution, gives a polarografic positive curve in the 95,83 per cent of cases and not clearly in the 4,17 of the other cases that we have tested. The uncertain cases must be necesary repeated with the employ of another diferent sensibility on the galvanometer of the polarografy, in order to made more evident the positiveness or negativiness of the experiments.

In the malignant thumors cases, the results are positives in the 100 per cent of the cases, what proves the advantages of the method in order to confirm the State of a thumoration before treated.

Thumors treated and cured, given a negative result in the 100 per cent of cases and in the which the cure is not total, but the evolution is favorable, the result es uncertain in the 100 per cent of cases. This conclusion is able to permit us the deduction that by means of polarografics it is possible to confirm the cure of a thumoration and the evolution of malignant thumors during the treatment.

In the not malignant thumors studied by us, the results has been negative in the 80 per cent of cases and uncertain in the 20 per cent. In the uncertain case it is necesary to repeat de polarografic curve with another sensibility and to prove the evolution of the process in the histologic examination cannot be realized.

In normal patients the results of the test are negatives in the 100 per cent of cases. Of this one and of the other two conclusions, it can be deduced that the negatives tests are not in favor of the diagnostics of malignant thumorations. In many febrile maladys, as the tuberculosis, typhus and in the lymphogranulomatosis, the results are positives in the 100 per cent of cases. What permit us to deduce that the differential diagnostic in all of this cases, must be realized by the specific methods of diagnostic.

In many others processes investigated, the result of the taste is positive in the 20 per cent of cases, by which reason are this the ones can be induced to a greatest number of diagnostical mistakes and in consequence it is necesary to have care of the possibility that some one process can exist giving positive results in the case of the now coincidence of the positive curve with the chemical diagnostics of the process.